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							- import {
 
- 	FileLoader,
 
- 	Loader,
 
- 	Matrix4,
 
- 	Vector3
 
- } from '../../../build/three.module.js';
 
- import * as fflate from '../libs/fflate.module.js';
 
- import { Volume } from '../misc/Volume.js';
 
- class NRRDLoader extends Loader {
 
- 	constructor( manager ) {
 
- 		super( manager );
 
- 	}
 
- 	load( url, onLoad, onProgress, onError ) {
 
- 		const scope = this;
 
- 		const loader = new FileLoader( scope.manager );
 
- 		loader.setPath( scope.path );
 
- 		loader.setResponseType( 'arraybuffer' );
 
- 		loader.setRequestHeader( scope.requestHeader );
 
- 		loader.setWithCredentials( scope.withCredentials );
 
- 		loader.load( url, function ( data ) {
 
- 			try {
 
- 				onLoad( scope.parse( data ) );
 
- 			} catch ( e ) {
 
- 				if ( onError ) {
 
- 					onError( e );
 
- 				} else {
 
- 					console.error( e );
 
- 				}
 
- 				scope.manager.itemError( url );
 
- 			}
 
- 		}, onProgress, onError );
 
- 	}
 
- 	parse( data ) {
 
- 		// this parser is largely inspired from the XTK NRRD parser : https://github.com/xtk/X
 
- 		let _data = data;
 
- 		let _dataPointer = 0;
 
- 		const _nativeLittleEndian = new Int8Array( new Int16Array( [ 1 ] ).buffer )[ 0 ] > 0;
 
- 		const _littleEndian = true;
 
- 		const headerObject = {};
 
- 		function scan( type, chunks ) {
 
- 			if ( chunks === undefined || chunks === null ) {
 
- 				chunks = 1;
 
- 			}
 
- 			let _chunkSize = 1;
 
- 			let _array_type = Uint8Array;
 
- 			switch ( type ) {
 
- 				// 1 byte data types
 
- 				case 'uchar':
 
- 					break;
 
- 				case 'schar':
 
- 					_array_type = Int8Array;
 
- 					break;
 
- 				// 2 byte data types
 
- 				case 'ushort':
 
- 					_array_type = Uint16Array;
 
- 					_chunkSize = 2;
 
- 					break;
 
- 				case 'sshort':
 
- 					_array_type = Int16Array;
 
- 					_chunkSize = 2;
 
- 					break;
 
- 				// 4 byte data types
 
- 				case 'uint':
 
- 					_array_type = Uint32Array;
 
- 					_chunkSize = 4;
 
- 					break;
 
- 				case 'sint':
 
- 					_array_type = Int32Array;
 
- 					_chunkSize = 4;
 
- 					break;
 
- 				case 'float':
 
- 					_array_type = Float32Array;
 
- 					_chunkSize = 4;
 
- 					break;
 
- 				case 'complex':
 
- 					_array_type = Float64Array;
 
- 					_chunkSize = 8;
 
- 					break;
 
- 				case 'double':
 
- 					_array_type = Float64Array;
 
- 					_chunkSize = 8;
 
- 					break;
 
- 			}
 
- 			// increase the data pointer in-place
 
- 			let _bytes = new _array_type( _data.slice( _dataPointer,
 
- 				_dataPointer += chunks * _chunkSize ) );
 
- 			// if required, flip the endianness of the bytes
 
- 			if ( _nativeLittleEndian != _littleEndian ) {
 
- 				// we need to flip here since the format doesn't match the native endianness
 
- 				_bytes = flipEndianness( _bytes, _chunkSize );
 
- 			}
 
- 			if ( chunks == 1 ) {
 
- 				// if only one chunk was requested, just return one value
 
- 				return _bytes[ 0 ];
 
- 			}
 
- 			// return the byte array
 
- 			return _bytes;
 
- 		}
 
- 		//Flips typed array endianness in-place. Based on https://github.com/kig/DataStream.js/blob/master/DataStream.js.
 
- 		function flipEndianness( array, chunkSize ) {
 
- 			const u8 = new Uint8Array( array.buffer, array.byteOffset, array.byteLength );
 
- 			for ( let i = 0; i < array.byteLength; i += chunkSize ) {
 
- 				for ( let j = i + chunkSize - 1, k = i; j > k; j --, k ++ ) {
 
- 					const tmp = u8[ k ];
 
- 					u8[ k ] = u8[ j ];
 
- 					u8[ j ] = tmp;
 
- 				}
 
- 			}
 
- 			return array;
 
- 		}
 
- 		//parse the header
 
- 		function parseHeader( header ) {
 
- 			let data, field, fn, i, l, m, _i, _len;
 
- 			const lines = header.split( /\r?\n/ );
 
- 			for ( _i = 0, _len = lines.length; _i < _len; _i ++ ) {
 
- 				l = lines[ _i ];
 
- 				if ( l.match( /NRRD\d+/ ) ) {
 
- 					headerObject.isNrrd = true;
 
- 				} else if ( l.match( /^#/ ) ) {
 
- 				} else if ( m = l.match( /(.*):(.*)/ ) ) {
 
- 					field = m[ 1 ].trim();
 
- 					data = m[ 2 ].trim();
 
- 					fn = _fieldFunctions[ field ];
 
- 					if ( fn ) {
 
- 						fn.call( headerObject, data );
 
- 					} else {
 
- 						headerObject[ field ] = data;
 
- 					}
 
- 				}
 
- 			}
 
- 			if ( ! headerObject.isNrrd ) {
 
- 				throw new Error( 'Not an NRRD file' );
 
- 			}
 
- 			if ( headerObject.encoding === 'bz2' || headerObject.encoding === 'bzip2' ) {
 
- 				throw new Error( 'Bzip is not supported' );
 
- 			}
 
- 			if ( ! headerObject.vectors ) {
 
- 				//if no space direction is set, let's use the identity
 
- 				headerObject.vectors = [ new Vector3( 1, 0, 0 ), new Vector3( 0, 1, 0 ), new Vector3( 0, 0, 1 ) ];
 
- 				//apply spacing if defined
 
- 				if ( headerObject.spacings ) {
 
- 					for ( i = 0; i <= 2; i ++ ) {
 
- 						if ( ! isNaN( headerObject.spacings[ i ] ) ) {
 
- 							headerObject.vectors[ i ].multiplyScalar( headerObject.spacings[ i ] );
 
- 						}
 
- 					}
 
- 				}
 
- 			}
 
- 		}
 
- 		//parse the data when registred as one of this type : 'text', 'ascii', 'txt'
 
- 		function parseDataAsText( data, start, end ) {
 
- 			let number = '';
 
- 			start = start || 0;
 
- 			end = end || data.length;
 
- 			let value;
 
- 			//length of the result is the product of the sizes
 
- 			const lengthOfTheResult = headerObject.sizes.reduce( function ( previous, current ) {
 
- 				return previous * current;
 
- 			}, 1 );
 
- 			let base = 10;
 
- 			if ( headerObject.encoding === 'hex' ) {
 
- 				base = 16;
 
- 			}
 
- 			const result = new headerObject.__array( lengthOfTheResult );
 
- 			let resultIndex = 0;
 
- 			let parsingFunction = parseInt;
 
- 			if ( headerObject.__array === Float32Array || headerObject.__array === Float64Array ) {
 
- 				parsingFunction = parseFloat;
 
- 			}
 
- 			for ( let i = start; i < end; i ++ ) {
 
- 				value = data[ i ];
 
- 				//if value is not a space
 
- 				if ( ( value < 9 || value > 13 ) && value !== 32 ) {
 
- 					number += String.fromCharCode( value );
 
- 				} else {
 
- 					if ( number !== '' ) {
 
- 						result[ resultIndex ] = parsingFunction( number, base );
 
- 						resultIndex ++;
 
- 					}
 
- 					number = '';
 
- 				}
 
- 			}
 
- 			if ( number !== '' ) {
 
- 				result[ resultIndex ] = parsingFunction( number, base );
 
- 				resultIndex ++;
 
- 			}
 
- 			return result;
 
- 		}
 
- 		const _bytes = scan( 'uchar', data.byteLength );
 
- 		const _length = _bytes.length;
 
- 		let _header = null;
 
- 		let _data_start = 0;
 
- 		let i;
 
- 		for ( i = 1; i < _length; i ++ ) {
 
- 			if ( _bytes[ i - 1 ] == 10 && _bytes[ i ] == 10 ) {
 
- 				// we found two line breaks in a row
 
- 				// now we know what the header is
 
- 				_header = this.parseChars( _bytes, 0, i - 2 );
 
- 				// this is were the data starts
 
- 				_data_start = i + 1;
 
- 				break;
 
- 			}
 
- 		}
 
- 		// parse the header
 
- 		parseHeader( _header );
 
- 		_data = _bytes.subarray( _data_start ); // the data without header
 
- 		if ( headerObject.encoding.substring( 0, 2 ) === 'gz' ) {
 
- 			// we need to decompress the datastream
 
- 			// here we start the unzipping and get a typed Uint8Array back
 
- 			_data = fflate.gunzipSync( new Uint8Array( _data ) );// eslint-disable-line no-undef
 
- 		} else if ( headerObject.encoding === 'ascii' || headerObject.encoding === 'text' || headerObject.encoding === 'txt' || headerObject.encoding === 'hex' ) {
 
- 			_data = parseDataAsText( _data );
 
- 		} else if ( headerObject.encoding === 'raw' ) {
 
- 			//we need to copy the array to create a new array buffer, else we retrieve the original arraybuffer with the header
 
- 			const _copy = new Uint8Array( _data.length );
 
- 			for ( let i = 0; i < _data.length; i ++ ) {
 
- 				_copy[ i ] = _data[ i ];
 
- 			}
 
- 			_data = _copy;
 
- 		}
 
- 		// .. let's use the underlying array buffer
 
- 		_data = _data.buffer;
 
- 		const volume = new Volume();
 
- 		volume.header = headerObject;
 
- 		//
 
- 		// parse the (unzipped) data to a datastream of the correct type
 
- 		//
 
- 		volume.data = new headerObject.__array( _data );
 
- 		// get the min and max intensities
 
- 		const min_max = volume.computeMinMax();
 
- 		const min = min_max[ 0 ];
 
- 		const max = min_max[ 1 ];
 
- 		// attach the scalar range to the volume
 
- 		volume.windowLow = min;
 
- 		volume.windowHigh = max;
 
- 		// get the image dimensions
 
- 		volume.dimensions = [ headerObject.sizes[ 0 ], headerObject.sizes[ 1 ], headerObject.sizes[ 2 ] ];
 
- 		volume.xLength = volume.dimensions[ 0 ];
 
- 		volume.yLength = volume.dimensions[ 1 ];
 
- 		volume.zLength = volume.dimensions[ 2 ];
 
- 		// Identify axis order in the space-directions matrix from the header if possible.
 
- 		if ( headerObject.vectors ) {
 
- 			const xIndex = headerObject.vectors.findIndex( vector => vector[ 0 ] !== 0 );
 
- 			const yIndex = headerObject.vectors.findIndex( vector => vector[ 1 ] !== 0 );
 
- 			const zIndex = headerObject.vectors.findIndex( vector => vector[ 2 ] !== 0 );
 
- 			const axisOrder = [];
 
- 			axisOrder[ xIndex ] = 'x';
 
- 			axisOrder[ yIndex ] = 'y';
 
- 			axisOrder[ zIndex ] = 'z';
 
- 			volume.axisOrder = axisOrder;
 
- 		} else {
 
- 			volume.axisOrder = [ 'x', 'y', 'z' ];
 
- 		}
 
- 		// spacing
 
- 		const spacingX = new Vector3().fromArray( headerObject.vectors[ 0 ] ).length();
 
- 		const spacingY = new Vector3().fromArray( headerObject.vectors[ 1 ] ).length();
 
- 		const spacingZ = new Vector3().fromArray( headerObject.vectors[ 2 ] ).length();
 
- 		volume.spacing = [ spacingX, spacingY, spacingZ ];
 
- 		// Create IJKtoRAS matrix
 
- 		volume.matrix = new Matrix4();
 
- 		const transitionMatrix = new Matrix4();
 
- 		if ( headerObject.space === 'left-posterior-superior' ) {
 
- 			transitionMatrix.set(
 
- 				- 1, 0, 0, 0,
 
- 				0, - 1, 0, 0,
 
- 				0, 0, 1, 0,
 
- 				0, 0, 0, 1
 
- 			);
 
- 		} else if ( headerObject.space === 'left-anterior-superior' ) {
 
- 			transitionMatrix.set(
 
- 				1, 0, 0, 0,
 
- 				0, 1, 0, 0,
 
- 				0, 0, - 1, 0,
 
- 				0, 0, 0, 1
 
- 			);
 
- 		}
 
- 		if ( ! headerObject.vectors ) {
 
- 			volume.matrix.set(
 
- 				1, 0, 0, 0,
 
- 				0, 1, 0, 0,
 
- 				0, 0, 1, 0,
 
- 				0, 0, 0, 1 );
 
- 		} else {
 
- 			const v = headerObject.vectors;
 
- 			const ijk_to_transition = new Matrix4().set(
 
- 				v[ 0 ][ 0 ], v[ 1 ][ 0 ], v[ 2 ][ 0 ], 0,
 
- 				v[ 0 ][ 1 ], v[ 1 ][ 1 ], v[ 2 ][ 1 ], 0,
 
- 				v[ 0 ][ 2 ], v[ 1 ][ 2 ], v[ 2 ][ 2 ], 0,
 
- 				0, 0, 0, 1
 
- 			);
 
- 			const transition_to_ras = new Matrix4().multiplyMatrices( ijk_to_transition, transitionMatrix );
 
- 			volume.matrix = transition_to_ras;
 
- 		}
 
- 		volume.inverseMatrix = new Matrix4();
 
- 		volume.inverseMatrix.copy( volume.matrix ).invert();
 
- 		volume.RASDimensions = new Vector3( volume.xLength, volume.yLength, volume.zLength ).applyMatrix4( volume.matrix ).round().toArray().map( Math.abs );
 
- 		// .. and set the default threshold
 
- 		// only if the threshold was not already set
 
- 		if ( volume.lowerThreshold === - Infinity ) {
 
- 			volume.lowerThreshold = min;
 
- 		}
 
- 		if ( volume.upperThreshold === Infinity ) {
 
- 			volume.upperThreshold = max;
 
- 		}
 
- 		return volume;
 
- 	}
 
- 	parseChars( array, start, end ) {
 
- 		// without borders, use the whole array
 
- 		if ( start === undefined ) {
 
- 			start = 0;
 
- 		}
 
- 		if ( end === undefined ) {
 
- 			end = array.length;
 
- 		}
 
- 		let output = '';
 
- 		// create and append the chars
 
- 		let i = 0;
 
- 		for ( i = start; i < end; ++ i ) {
 
- 			output += String.fromCharCode( array[ i ] );
 
- 		}
 
- 		return output;
 
- 	}
 
- }
 
- const _fieldFunctions = {
 
- 	type: function ( data ) {
 
- 		switch ( data ) {
 
- 			case 'uchar':
 
- 			case 'unsigned char':
 
- 			case 'uint8':
 
- 			case 'uint8_t':
 
- 				this.__array = Uint8Array;
 
- 				break;
 
- 			case 'signed char':
 
- 			case 'int8':
 
- 			case 'int8_t':
 
- 				this.__array = Int8Array;
 
- 				break;
 
- 			case 'short':
 
- 			case 'short int':
 
- 			case 'signed short':
 
- 			case 'signed short int':
 
- 			case 'int16':
 
- 			case 'int16_t':
 
- 				this.__array = Int16Array;
 
- 				break;
 
- 			case 'ushort':
 
- 			case 'unsigned short':
 
- 			case 'unsigned short int':
 
- 			case 'uint16':
 
- 			case 'uint16_t':
 
- 				this.__array = Uint16Array;
 
- 				break;
 
- 			case 'int':
 
- 			case 'signed int':
 
- 			case 'int32':
 
- 			case 'int32_t':
 
- 				this.__array = Int32Array;
 
- 				break;
 
- 			case 'uint':
 
- 			case 'unsigned int':
 
- 			case 'uint32':
 
- 			case 'uint32_t':
 
- 				this.__array = Uint32Array;
 
- 				break;
 
- 			case 'float':
 
- 				this.__array = Float32Array;
 
- 				break;
 
- 			case 'double':
 
- 				this.__array = Float64Array;
 
- 				break;
 
- 			default:
 
- 				throw new Error( 'Unsupported NRRD data type: ' + data );
 
- 		}
 
- 		return this.type = data;
 
- 	},
 
- 	endian: function ( data ) {
 
- 		return this.endian = data;
 
- 	},
 
- 	encoding: function ( data ) {
 
- 		return this.encoding = data;
 
- 	},
 
- 	dimension: function ( data ) {
 
- 		return this.dim = parseInt( data, 10 );
 
- 	},
 
- 	sizes: function ( data ) {
 
- 		let i;
 
- 		return this.sizes = ( function () {
 
- 			const _ref = data.split( /\s+/ );
 
- 			const _results = [];
 
- 			for ( let _i = 0, _len = _ref.length; _i < _len; _i ++ ) {
 
- 				i = _ref[ _i ];
 
- 				_results.push( parseInt( i, 10 ) );
 
- 			}
 
- 			return _results;
 
- 		} )();
 
- 	},
 
- 	space: function ( data ) {
 
- 		return this.space = data;
 
- 	},
 
- 	'space origin': function ( data ) {
 
- 		return this.space_origin = data.split( '(' )[ 1 ].split( ')' )[ 0 ].split( ',' );
 
- 	},
 
- 	'space directions': function ( data ) {
 
- 		let f, v;
 
- 		const parts = data.match( /\(.*?\)/g );
 
- 		return this.vectors = ( function () {
 
- 			const _results = [];
 
- 			for ( let _i = 0, _len = parts.length; _i < _len; _i ++ ) {
 
- 				v = parts[ _i ];
 
- 				_results.push( ( function () {
 
- 					const _ref = v.slice( 1, - 1 ).split( /,/ );
 
- 					const _results2 = [];
 
- 					for ( let _j = 0, _len2 = _ref.length; _j < _len2; _j ++ ) {
 
- 						f = _ref[ _j ];
 
- 						_results2.push( parseFloat( f ) );
 
- 					}
 
- 					return _results2;
 
- 				} )() );
 
- 			}
 
- 			return _results;
 
- 		} )();
 
- 	},
 
- 	spacings: function ( data ) {
 
- 		let f;
 
- 		const parts = data.split( /\s+/ );
 
- 		return this.spacings = ( function () {
 
- 			const _results = [];
 
- 			for ( let _i = 0, _len = parts.length; _i < _len; _i ++ ) {
 
- 				f = parts[ _i ];
 
- 				_results.push( parseFloat( f ) );
 
- 			}
 
- 			return _results;
 
- 		} )();
 
- 	}
 
- };
 
- export { NRRDLoader };
 
 
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