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							- ( function () {
 
- 	class NRRDLoader extends THREE.Loader {
 
- 		constructor( manager ) {
 
- 			super( manager );
 
- 		}
 
- 		load( url, onLoad, onProgress, onError ) {
 
- 			const scope = this;
 
- 			const loader = new THREE.FileLoader( scope.manager );
 
- 			loader.setPath( scope.path );
 
- 			loader.setResponseType( 'arraybuffer' );
 
- 			loader.setRequestHeader( scope.requestHeader );
 
- 			loader.setWithCredentials( scope.withCredentials );
 
- 			loader.load( url, function ( data ) {
 
- 				try {
 
- 					onLoad( scope.parse( data ) );
 
- 				} catch ( e ) {
 
- 					if ( onError ) {
 
- 						onError( e );
 
- 					} else {
 
- 						console.error( e );
 
- 					}
 
- 					scope.manager.itemError( url );
 
- 				}
 
- 			}, onProgress, onError );
 
- 		}
 
- 		parse( data ) {
 
- 			// this parser is largely inspired from the XTK NRRD parser : https://github.com/xtk/X
 
- 			let _data = data;
 
- 			let _dataPointer = 0;
 
- 			const _nativeLittleEndian = new Int8Array( new Int16Array( [ 1 ] ).buffer )[ 0 ] > 0;
 
- 			const _littleEndian = true;
 
- 			const headerObject = {};
 
- 			function scan( type, chunks ) {
 
- 				if ( chunks === undefined || chunks === null ) {
 
- 					chunks = 1;
 
- 				}
 
- 				let _chunkSize = 1;
 
- 				let _array_type = Uint8Array;
 
- 				switch ( type ) {
 
- 					// 1 byte data types
 
- 					case 'uchar':
 
- 						break;
 
- 					case 'schar':
 
- 						_array_type = Int8Array;
 
- 						break;
 
- 						// 2 byte data types
 
- 					case 'ushort':
 
- 						_array_type = Uint16Array;
 
- 						_chunkSize = 2;
 
- 						break;
 
- 					case 'sshort':
 
- 						_array_type = Int16Array;
 
- 						_chunkSize = 2;
 
- 						break;
 
- 						// 4 byte data types
 
- 					case 'uint':
 
- 						_array_type = Uint32Array;
 
- 						_chunkSize = 4;
 
- 						break;
 
- 					case 'sint':
 
- 						_array_type = Int32Array;
 
- 						_chunkSize = 4;
 
- 						break;
 
- 					case 'float':
 
- 						_array_type = Float32Array;
 
- 						_chunkSize = 4;
 
- 						break;
 
- 					case 'complex':
 
- 						_array_type = Float64Array;
 
- 						_chunkSize = 8;
 
- 						break;
 
- 					case 'double':
 
- 						_array_type = Float64Array;
 
- 						_chunkSize = 8;
 
- 						break;
 
- 				} // increase the data pointer in-place
 
- 				let _bytes = new _array_type( _data.slice( _dataPointer, _dataPointer += chunks * _chunkSize ) ); // if required, flip the endianness of the bytes
 
- 				if ( _nativeLittleEndian != _littleEndian ) {
 
- 					// we need to flip here since the format doesn't match the native endianness
 
- 					_bytes = flipEndianness( _bytes, _chunkSize );
 
- 				}
 
- 				if ( chunks == 1 ) {
 
- 					// if only one chunk was requested, just return one value
 
- 					return _bytes[ 0 ];
 
- 				} // return the byte array
 
- 				return _bytes;
 
- 			} //Flips typed array endianness in-place. Based on https://github.com/kig/DataStream.js/blob/master/DataStream.js.
 
- 			function flipEndianness( array, chunkSize ) {
 
- 				const u8 = new Uint8Array( array.buffer, array.byteOffset, array.byteLength );
 
- 				for ( let i = 0; i < array.byteLength; i += chunkSize ) {
 
- 					for ( let j = i + chunkSize - 1, k = i; j > k; j --, k ++ ) {
 
- 						const tmp = u8[ k ];
 
- 						u8[ k ] = u8[ j ];
 
- 						u8[ j ] = tmp;
 
- 					}
 
- 				}
 
- 				return array;
 
- 			} //parse the header
 
- 			function parseHeader( header ) {
 
- 				let data, field, fn, i, l, m, _i, _len;
 
- 				const lines = header.split( /\r?\n/ );
 
- 				for ( _i = 0, _len = lines.length; _i < _len; _i ++ ) {
 
- 					l = lines[ _i ];
 
- 					if ( l.match( /NRRD\d+/ ) ) {
 
- 						headerObject.isNrrd = true;
 
- 					} else if ( l.match( /^#/ ) ) {} else if ( m = l.match( /(.*):(.*)/ ) ) {
 
- 						field = m[ 1 ].trim();
 
- 						data = m[ 2 ].trim();
 
- 						fn = _fieldFunctions[ field ];
 
- 						if ( fn ) {
 
- 							fn.call( headerObject, data );
 
- 						} else {
 
- 							headerObject[ field ] = data;
 
- 						}
 
- 					}
 
- 				}
 
- 				if ( ! headerObject.isNrrd ) {
 
- 					throw new Error( 'Not an NRRD file' );
 
- 				}
 
- 				if ( headerObject.encoding === 'bz2' || headerObject.encoding === 'bzip2' ) {
 
- 					throw new Error( 'Bzip is not supported' );
 
- 				}
 
- 				if ( ! headerObject.vectors ) {
 
- 					//if no space direction is set, let's use the identity
 
- 					headerObject.vectors = [ new THREE.Vector3( 1, 0, 0 ), new THREE.Vector3( 0, 1, 0 ), new THREE.Vector3( 0, 0, 1 ) ]; //apply spacing if defined
 
- 					if ( headerObject.spacings ) {
 
- 						for ( i = 0; i <= 2; i ++ ) {
 
- 							if ( ! isNaN( headerObject.spacings[ i ] ) ) {
 
- 								headerObject.vectors[ i ].multiplyScalar( headerObject.spacings[ i ] );
 
- 							}
 
- 						}
 
- 					}
 
- 				}
 
- 			} //parse the data when registred as one of this type : 'text', 'ascii', 'txt'
 
- 			function parseDataAsText( data, start, end ) {
 
- 				let number = '';
 
- 				start = start || 0;
 
- 				end = end || data.length;
 
- 				let value; //length of the result is the product of the sizes
 
- 				const lengthOfTheResult = headerObject.sizes.reduce( function ( previous, current ) {
 
- 					return previous * current;
 
- 				}, 1 );
 
- 				let base = 10;
 
- 				if ( headerObject.encoding === 'hex' ) {
 
- 					base = 16;
 
- 				}
 
- 				const result = new headerObject.__array( lengthOfTheResult );
 
- 				let resultIndex = 0;
 
- 				let parsingFunction = parseInt;
 
- 				if ( headerObject.__array === Float32Array || headerObject.__array === Float64Array ) {
 
- 					parsingFunction = parseFloat;
 
- 				}
 
- 				for ( let i = start; i < end; i ++ ) {
 
- 					value = data[ i ]; //if value is not a space
 
- 					if ( ( value < 9 || value > 13 ) && value !== 32 ) {
 
- 						number += String.fromCharCode( value );
 
- 					} else {
 
- 						if ( number !== '' ) {
 
- 							result[ resultIndex ] = parsingFunction( number, base );
 
- 							resultIndex ++;
 
- 						}
 
- 						number = '';
 
- 					}
 
- 				}
 
- 				if ( number !== '' ) {
 
- 					result[ resultIndex ] = parsingFunction( number, base );
 
- 					resultIndex ++;
 
- 				}
 
- 				return result;
 
- 			}
 
- 			const _bytes = scan( 'uchar', data.byteLength );
 
- 			const _length = _bytes.length;
 
- 			let _header = null;
 
- 			let _data_start = 0;
 
- 			let i;
 
- 			for ( i = 1; i < _length; i ++ ) {
 
- 				if ( _bytes[ i - 1 ] == 10 && _bytes[ i ] == 10 ) {
 
- 					// we found two line breaks in a row
 
- 					// now we know what the header is
 
- 					_header = this.parseChars( _bytes, 0, i - 2 ); // this is were the data starts
 
- 					_data_start = i + 1;
 
- 					break;
 
- 				}
 
- 			} // parse the header
 
- 			parseHeader( _header );
 
- 			_data = _bytes.subarray( _data_start ); // the data without header
 
- 			if ( headerObject.encoding.substring( 0, 2 ) === 'gz' ) {
 
- 				// we need to decompress the datastream
 
- 				// here we start the unzipping and get a typed Uint8Array back
 
- 				_data = fflate.gunzipSync( new Uint8Array( _data ) ); // eslint-disable-line no-undef
 
- 			} else if ( headerObject.encoding === 'ascii' || headerObject.encoding === 'text' || headerObject.encoding === 'txt' || headerObject.encoding === 'hex' ) {
 
- 				_data = parseDataAsText( _data );
 
- 			} else if ( headerObject.encoding === 'raw' ) {
 
- 				//we need to copy the array to create a new array buffer, else we retrieve the original arraybuffer with the header
 
- 				const _copy = new Uint8Array( _data.length );
 
- 				for ( let i = 0; i < _data.length; i ++ ) {
 
- 					_copy[ i ] = _data[ i ];
 
- 				}
 
- 				_data = _copy;
 
- 			} // .. let's use the underlying array buffer
 
- 			_data = _data.buffer;
 
- 			const volume = new THREE.Volume();
 
- 			volume.header = headerObject; //
 
- 			// parse the (unzipped) data to a datastream of the correct type
 
- 			//
 
- 			volume.data = new headerObject.__array( _data ); // get the min and max intensities
 
- 			const min_max = volume.computeMinMax();
 
- 			const min = min_max[ 0 ];
 
- 			const max = min_max[ 1 ]; // attach the scalar range to the volume
 
- 			volume.windowLow = min;
 
- 			volume.windowHigh = max; // get the image dimensions
 
- 			volume.dimensions = [ headerObject.sizes[ 0 ], headerObject.sizes[ 1 ], headerObject.sizes[ 2 ] ];
 
- 			volume.xLength = volume.dimensions[ 0 ];
 
- 			volume.yLength = volume.dimensions[ 1 ];
 
- 			volume.zLength = volume.dimensions[ 2 ]; // Identify axis order in the space-directions matrix from the header if possible.
 
- 			if ( headerObject.vectors ) {
 
- 				const xIndex = headerObject.vectors.findIndex( vector => vector[ 0 ] !== 0 );
 
- 				const yIndex = headerObject.vectors.findIndex( vector => vector[ 1 ] !== 0 );
 
- 				const zIndex = headerObject.vectors.findIndex( vector => vector[ 2 ] !== 0 );
 
- 				const axisOrder = [];
 
- 				axisOrder[ xIndex ] = 'x';
 
- 				axisOrder[ yIndex ] = 'y';
 
- 				axisOrder[ zIndex ] = 'z';
 
- 				volume.axisOrder = axisOrder;
 
- 			} else {
 
- 				volume.axisOrder = [ 'x', 'y', 'z' ];
 
- 			} // spacing
 
- 			const spacingX = new THREE.Vector3().fromArray( headerObject.vectors[ 0 ] ).length();
 
- 			const spacingY = new THREE.Vector3().fromArray( headerObject.vectors[ 1 ] ).length();
 
- 			const spacingZ = new THREE.Vector3().fromArray( headerObject.vectors[ 2 ] ).length();
 
- 			volume.spacing = [ spacingX, spacingY, spacingZ ]; // Create IJKtoRAS matrix
 
- 			volume.matrix = new THREE.Matrix4();
 
- 			const transitionMatrix = new THREE.Matrix4();
 
- 			if ( headerObject.space === 'left-posterior-superior' ) {
 
- 				transitionMatrix.set( - 1, 0, 0, 0, 0, - 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1 );
 
- 			} else if ( headerObject.space === 'left-anterior-superior' ) {
 
- 				transitionMatrix.set( 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, - 1, 0, 0, 0, 0, 1 );
 
- 			}
 
- 			if ( ! headerObject.vectors ) {
 
- 				volume.matrix.set( 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1 );
 
- 			} else {
 
- 				const v = headerObject.vectors;
 
- 				const ijk_to_transition = new THREE.Matrix4().set( v[ 0 ][ 0 ], v[ 1 ][ 0 ], v[ 2 ][ 0 ], 0, v[ 0 ][ 1 ], v[ 1 ][ 1 ], v[ 2 ][ 1 ], 0, v[ 0 ][ 2 ], v[ 1 ][ 2 ], v[ 2 ][ 2 ], 0, 0, 0, 0, 1 );
 
- 				const transition_to_ras = new THREE.Matrix4().multiplyMatrices( ijk_to_transition, transitionMatrix );
 
- 				volume.matrix = transition_to_ras;
 
- 			}
 
- 			volume.inverseMatrix = new THREE.Matrix4();
 
- 			volume.inverseMatrix.copy( volume.matrix ).invert();
 
- 			volume.RASDimensions = new THREE.Vector3( volume.xLength, volume.yLength, volume.zLength ).applyMatrix4( volume.matrix ).round().toArray().map( Math.abs ); // .. and set the default threshold
 
- 			// only if the threshold was not already set
 
- 			if ( volume.lowerThreshold === - Infinity ) {
 
- 				volume.lowerThreshold = min;
 
- 			}
 
- 			if ( volume.upperThreshold === Infinity ) {
 
- 				volume.upperThreshold = max;
 
- 			}
 
- 			return volume;
 
- 		}
 
- 		parseChars( array, start, end ) {
 
- 			// without borders, use the whole array
 
- 			if ( start === undefined ) {
 
- 				start = 0;
 
- 			}
 
- 			if ( end === undefined ) {
 
- 				end = array.length;
 
- 			}
 
- 			let output = ''; // create and append the chars
 
- 			let i = 0;
 
- 			for ( i = start; i < end; ++ i ) {
 
- 				output += String.fromCharCode( array[ i ] );
 
- 			}
 
- 			return output;
 
- 		}
 
- 	}
 
- 	const _fieldFunctions = {
 
- 		type: function ( data ) {
 
- 			switch ( data ) {
 
- 				case 'uchar':
 
- 				case 'unsigned char':
 
- 				case 'uint8':
 
- 				case 'uint8_t':
 
- 					this.__array = Uint8Array;
 
- 					break;
 
- 				case 'signed char':
 
- 				case 'int8':
 
- 				case 'int8_t':
 
- 					this.__array = Int8Array;
 
- 					break;
 
- 				case 'short':
 
- 				case 'short int':
 
- 				case 'signed short':
 
- 				case 'signed short int':
 
- 				case 'int16':
 
- 				case 'int16_t':
 
- 					this.__array = Int16Array;
 
- 					break;
 
- 				case 'ushort':
 
- 				case 'unsigned short':
 
- 				case 'unsigned short int':
 
- 				case 'uint16':
 
- 				case 'uint16_t':
 
- 					this.__array = Uint16Array;
 
- 					break;
 
- 				case 'int':
 
- 				case 'signed int':
 
- 				case 'int32':
 
- 				case 'int32_t':
 
- 					this.__array = Int32Array;
 
- 					break;
 
- 				case 'uint':
 
- 				case 'unsigned int':
 
- 				case 'uint32':
 
- 				case 'uint32_t':
 
- 					this.__array = Uint32Array;
 
- 					break;
 
- 				case 'float':
 
- 					this.__array = Float32Array;
 
- 					break;
 
- 				case 'double':
 
- 					this.__array = Float64Array;
 
- 					break;
 
- 				default:
 
- 					throw new Error( 'Unsupported NRRD data type: ' + data );
 
- 			}
 
- 			return this.type = data;
 
- 		},
 
- 		endian: function ( data ) {
 
- 			return this.endian = data;
 
- 		},
 
- 		encoding: function ( data ) {
 
- 			return this.encoding = data;
 
- 		},
 
- 		dimension: function ( data ) {
 
- 			return this.dim = parseInt( data, 10 );
 
- 		},
 
- 		sizes: function ( data ) {
 
- 			let i;
 
- 			return this.sizes = function () {
 
- 				const _ref = data.split( /\s+/ );
 
- 				const _results = [];
 
- 				for ( let _i = 0, _len = _ref.length; _i < _len; _i ++ ) {
 
- 					i = _ref[ _i ];
 
- 					_results.push( parseInt( i, 10 ) );
 
- 				}
 
- 				return _results;
 
- 			}();
 
- 		},
 
- 		space: function ( data ) {
 
- 			return this.space = data;
 
- 		},
 
- 		'space origin': function ( data ) {
 
- 			return this.space_origin = data.split( '(' )[ 1 ].split( ')' )[ 0 ].split( ',' );
 
- 		},
 
- 		'space directions': function ( data ) {
 
- 			let f, v;
 
- 			const parts = data.match( /\(.*?\)/g );
 
- 			return this.vectors = function () {
 
- 				const _results = [];
 
- 				for ( let _i = 0, _len = parts.length; _i < _len; _i ++ ) {
 
- 					v = parts[ _i ];
 
- 					_results.push( function () {
 
- 						const _ref = v.slice( 1, - 1 ).split( /,/ );
 
- 						const _results2 = [];
 
- 						for ( let _j = 0, _len2 = _ref.length; _j < _len2; _j ++ ) {
 
- 							f = _ref[ _j ];
 
- 							_results2.push( parseFloat( f ) );
 
- 						}
 
- 						return _results2;
 
- 					}() );
 
- 				}
 
- 				return _results;
 
- 			}();
 
- 		},
 
- 		spacings: function ( data ) {
 
- 			let f;
 
- 			const parts = data.split( /\s+/ );
 
- 			return this.spacings = function () {
 
- 				const _results = [];
 
- 				for ( let _i = 0, _len = parts.length; _i < _len; _i ++ ) {
 
- 					f = parts[ _i ];
 
- 					_results.push( parseFloat( f ) );
 
- 				}
 
- 				return _results;
 
- 			}();
 
- 		}
 
- 	};
 
- 	THREE.NRRDLoader = NRRDLoader;
 
- } )();
 
 
  |